|Column I||Column II|
|(i) primary strucutre||(a) Special arrangement of polypeptide subunits|
|(ii) Secondary strucutre||(b) strucure of amino acid|
|(iii) Tertiary strucre||(c) Folding of peptide chains|
|(iv) Quaternary stucture||(d) Sequence of amino acids|
|(e) Fibrous of globular nature|
b) When a protein in its native form, is subjected to physical change like change in temperature or chemical change like change in pH, the hydrogen bonds are disturbed. Due to this, globules unfold and helix get uncoiled and protein loses its biological activity. This is called denaturation of protein.