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ADA deficiency is permanently cured by gene therapy.

1. Expand ADA.

2. Write its normal function in human body.

3. If gene for ADA is deleted the person will become susceptible to attack of pathogens and die of ordinary diseases. By analysing the given statement can you explain the role of ADA.

4. Can you suggest alternative methods for curing the same disease?

1 Answer

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1. Adenosine deaminase

2. It is a crucial enzyme for the immune system to function.

3. The patients have non-functioning T-  Lymphocytes. So they cannot produce immune responses against invading pathogens.

4. Yes. Gene therapy is used for permanent curing of ADA deficiency.

There are two methods for treatment of ADA deficiency.

  • by bone-marrow transplantation
  • and by enzyme replacement therapy.

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