1. Bacillus thurungenesis produce a protein Cry protein coded by the cry gene. This protein kill certain insects like lepidopterarns (tobaccobud worm), boll worms, dipterans like mosquitoes.
These genes are isolated from Bacillus thuringenesis and incorporated into several crop plants like cotton. There are specific cry gene for specific toxin and each toxin controls or destroys specific insect.
2. Protein crystals solubilise only in the presence of alkaline pH but stomach of human body contains acidic pH .So it doesn’t make any harmful effect in humans.