Some cells in the adult animals do not appear to exhibit division (e.g., heart cells and many other cells divide only occasionally, as needed to replace cells that have been lost because of injury or cell death.
These cells do not divide further exit G1 phase to enter an inactive stage called quiescent stage (G0) of the cell cycle. Cells in this stage remain metabolically active but no longer proliferate unless called on to do so depending on the requirement of the organism.
