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Oxidative decarboxylation of pyruvate requires

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The oxidative decarboxylation of Pyruvate to form Acetyl-CoA is the link between Glycolysis and the Citric acid cycle.It is an irreversible oxidation process in which the carboxyl group is removed from pyruvate as a molecule of CO2 and the two remaining carbons become the acetyl group of Acetyl-CoA.

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