Question

Which of the following statements is/are correct?

(a) Bilirubin is transported in blood by being attached to plasma albumin

(b) Bilirubin is insoluble in water

(c) Both (a) and (b) are correct

(d) None of the above

Answer 1

Answer is : (c) Both (a) and (b) are correct

Bilirubin is produced in the macrophage-monocyte system by the breakdown of haemoglobin to biliverdin and then bilirubin. It is carried to the liver by attaching to the albumin as it is insoluble in water. In liver, bilirubin is conjugated with glucuronic acid by the enzyme glucuronyltransferase, making it soluble in water.