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Explain the major changes taking place during the three trimesters of pregnancy in woman.

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The pregnancy period of approximately nine months (280 days) is divided into three trimesters of three months each. 

1. First Trimester : (From fertilization to 12th week) 

  • During first trimester there are radical changes in the body of mother as well as in the embryo. 
  • The embryo receives nutrients in the first 2-4 weeks directly from the endometrium. 
  • It is the main period of organogenesis and the development of body organs. 
  • By the end of eight weeks, the major structures found in the adult are formed in the embryo in a rudimentary form. It is now called foetus and is about 3 cm long.
  • Arms, hands, fingers, feet, toes, CNS, excretory and circulatory system including heart are formed and begins to work. 
  • Progesterone level becomes high and menstrual cycle is suspended till the end of pregnancy. 
  • At the end of first trimester foetus is about 7-10 cm long. 
  • The maternal part of placenta grows, the uterus becomes larger. In this period, the mother experiences morning sickness, (nausea, vomiting, mood swings, etc.)

2. Second Trimester: (From 13th to 26th week) 

  • The foetus is very active and grows to about 30 cm. 
  • The uterus grows enough for the pregnancy to become obvious.
  • Hormone levels stabilize as hCG declines, the corpus luteum deteriorates and the placenta completely takes over the production of progesterone which maintains the pregnancy.
  • Head has hair, eyebrows and eyelashes appear, pinnae are distinct. Baby’s movement can be easily felt by the mother. 
  • The baby reaches half the size of a new born.

3. Third Trimester: (From 27th week till the parturition) 

  • Foetus grows to about 50 cm in length and about 3-4 kg in weight. 
  • As the foetus grows, the uterus expands around it, the mother’s abdominal organs become compressed and displaced, leading to frequent urination, digestive blockages and strain in the back muscles. 
  • At the end of third trimester the foetus becomes fully developed and ready for parturition.

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