(1) The technique of protecting or blocking group is commonly used in organic synthesis. Finally on completion of reaction deprotection of the group is required. This leads to unnecessary increase in the number of steps and decreased atom economy.
(2) The green chemistry principle aims to develop processes to avoid necessary steps i.e. (minimization of steps). When biocatalyst is used very often there is no need for protection of selective group. For example, conversion of mhydroxyl benzaldehyde to mhydroxybenzoic acid.
