1. The rate of transmission of impulse is higher in long and thick nerves.
2. It is higher in warm blooded animals [homeotherms] than in cold blooded animal [poikilotherms].
3. The velocity of transmission is higher in voluntary fibres (100- 120 m/second in man) as opposed to autonomic or involuntary nerves (10-20 m/second).
4. It is faster in medullated nerve fibre [up to 150 m/s], as the impulse has to jump from one node of Ranvier to the next as compared with nonmedullated nerve fibre [10-25 m/s]
