Question

A youth in his twenties met with an accident and succumbed to the injuries. His parents agreed to donate his organs. List any two essential clinical steps to be undertaken before any organ transplant. Why is the transplant rejected sometimes ? What views would you share with your health club members to promote organ donation ?

Answer 1

1. Blood group matching of donor. 2. Tissue Matching.
2. The grafts are rejected some times because of the cell mediated immunity involving the T-lymphocytes. The T-lymphocytes are responsible for the body to differentiate self and non-self leading to graft rejection. The views to be shared with health club members regarding organ donation are :
(i) Organ donation is a healthy practice and is life saving for those in need.
(ii) With the availability of immune suppressants like cyclosporine A the acceptability of donor organs in recipients has increased.