Question

The early algorithms based their prediction on hydrophobicity scales.

(a) True

(b) False

The question was asked in an online quiz.

My question is based upon Secondary Structure Prediction for Transmembrane Proteins in chapter Secondary Structure Prediction of Bioinformatics

Answer 1

The correct choice is (a) True

The best I can explain: A number of algorithms for identifying transmembrane helices have been developed where the early algorithms based their prediction on hydrophobicity scales. They typically scan a window of seventeen to twenty-five residues and assign membrane spans based on hydrophobicity scores. Some are also able to determine the orientation of the membrane helices based on the positive-inside rule.