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Annotation involves identifying open reading frames in the genome sequence.

(a) True

(b) False

This question was addressed to me during an interview.

The origin of the question is Genome Anatomy in portion Collecting & Storing Sequences in Laboratory of Bioinformatics

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Correct choice is (a) True

Best explanation: It is done by using the predicted protein as query sequences in a database similarity search. It further adds significant matches to the genome sequence entry in the sequence database.

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