Question

In Property-based measures, displaying physical properties on the molecular surface of molecules can help to guide molecular docking.

(a) True

(b) False

This question was posed to me during an interview for a job.

This interesting question is from Molecular Complementarity topic in chapter Predicting the Structure of Protein – Biomolecular Interactions of Bioinformatics

Answer 1

Correct answer is (a) True

To explain: Indeed in many cases, displaying physical properties on the molecular surface of molecules can help to guide molecular docking. Alternatively sequence conservation might also help, particularly where a homologous family of proteins maintain a specific binding partner.