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Who was the first to synthesize DNA in the laboratory?
1. Randy Schekman
2. Stanley Miller
3. Harold Urey
4. Arthur Kornberg

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Correct Answer - Option 4 : Arthur Kornberg

The Correct Answer is Arthur Kornberg.

  • Arthur Kornberg was an American biochemist who won the Nobel Prize in Physiology or Medicine 1959 for his discovery of "the mechanisms in the biological synthesis of deoxyribonucleic acid (DNA)" together with Dr. Severo Ochoa of New York University.
  • Randy Wayne Schekman is an American cell biologist at the University of California, Berkeley and former editor-in-chief of Proceedings of the National Academy of Sciences and Annual Review of Cell and Developmental Biology.
  • Stanley Lloyd Miller was an American chemist who made landmark experiments in the origin of life by demonstrating that a wide range of vital organic compounds can be synthesized by fairly simple chemical processes from inorganic substances.
  • Harold Clayton Urey was an American physical chemist whose pioneering work on isotopes earned him the Nobel Prize in Chemistry in 1934 for the discovery of deuterium.

  • DNA synthesis is the natural or synthetic composition of deoxyribonucleic acid (DNA) molecules. DNA is a macromolecule composed of nucleotide units, which are joined by covalent bonds and hydrogen bonds in a repeating structure.
  • DNA synthesis occurs in all eukaryotes and prokaryotes, as well as some viruses. 
  • Arthur Kornberg was the first to isolate DNA polymerase, the enzyme that assembles DNA from its components, and the first to synthesize DNA in a test tube, which earned him a Nobel Prize in 1959.

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