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Biologically, marriage should be avoided in between:
1. Rh– male and Rh– female
2. Rh+ male and Rh– female
3. Rh+ male and Rh+ female
4. None of the above

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Correct Answer - Option 2 : Rh+ male and Rh– female

Concept:

  • Each person has a blood type (O, A, B, or AB). Everyone also has an Rh factor (positive or negative).
  • The Rh factor is a protein on the covering of the red blood cells.
  • If the Rh factor protein is on the cells, the person is Rh-positive.
  • If there’s no Rh factor protein, the person is Rh-negative.

Explanation:

  • There can be a problem when an Rh-negative mother has a baby with an Rh-positive father.
  • If the baby's Rh factor is positive, like his or her father's, this can be a serious issue as, during the delivery of the first child, there is a possibility of exposure of the maternal blood to small amounts of the Rh+ve blood from the foetus.
  • In such cases, the mother starts preparing antibodies against Rh antigen in her blood.
  • In the case of her subsequent pregnancies, the Rh antibodies from the mother (Rh-ve) can leak into the blood of the foetus (Rh+ve) and destroy the foetal RBCs.
  • This could be fatal to the foetus or could cause severe anaemia and jaundice to the baby. This condition is called erythroblastosis foetalis
  • ​Thus Biologically, ''marriage should be avoided in between a Rh+ male and Rh– female''

​ 

  • Erythroblastosis foetalis can be avoided by administering anti-Rh antibodies to the mother immediately after the delivery of the first child.

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