Question

Deficiency of which of the following Vitamins causes pernicious anaemia?
1. Vitamin K
2. Vitamin E
3. Vitamin B₁₂
4. Vitamin B₆

Answer 1

Correct Answer - Option 3 : Vitamin B₁₂

Concept:

• A medical condition in which there is a shortage of healthy RBCs in the body is called Pernicious anemia. It is caused due to the deficiency of Vitamin B12.
• Pernicious anemia is a very rare and fatal disease.
•  pernicious anemia is a type of anemia that lack the  Intrinsic factor (IF)

​Explanation:

• Deficiency of Vitamins can cause several diseases like scurvy, night blindness, anemia, etc.
• Pernicious Anemia is caused due to the deficiency of Vitamin B12.
• The chemical name of Vitamin B12 is CyanoCobalamin.
• It is used for the production of RBC as we know that RBC contains Hemoglobin which contains Iron and hence the deficiency also results in Anemia.
• It is mostly found in non-vegetarian food like red meat hence it is known as Nonvegetarian Vitamin.
• It also works along with Vitamin B9 and is quite useful for pregnant ladies.

• Vitamin K is responsible for blood coagulation. Without vitamin K, blood coagulation is seriously impaired, and uncontrolled bleeding occurs. 
• Vitamin B6 forms part of the coenzyme for amino acid synthesis and glycogen synthesis. It helps in nerve function and RBC formation. Its deficiency causes skin lesions, disturbance of CNS, and anemia.
• Vitamin E is also known as Tocopherol its deficiency can result in less fertility.
• Vegetable oil, Sprouted wheat, Leafy vegetables, Milk, Butter, etc are the major sources of Vitamin- E.