Substances that interface with microtubule function interfare with cell division because....
(a) Microtubules are distributed equally in the new cells
(b) Microtubules are involved in precise separate set of chromosomes get into each daughter cells.
(c) Without microtubules, cytokinesis cannot take place and a membrane is formed.
(d) Microtubules are essential for the disappearince of the nuclear membrane and without them the chromosomes have to stay close together within the nuclear membrave to be able to separate into two new nuclei.