One can imagine a cycle like an analog clock at which at 0 o’clock is the beginning and the end of the menstrual cycle and that 6 o’clock corresponds to the 14h day of the cycle.
At 0 o’clock the menses and so the menstrual cycle begins and FSH blood level begins to increase. Around 2 o’clock the maturing follicles under FSH action are already secreting estrogen and the endometrium is thickening. Around 3 o’clock estrogen is intensely stimulating the increase of LH blood level. At 6 o’clock (the 14th day) LH is at its maximum concentration and FSH also at high levels to promote ovulation,
LH then stimulates the formation of the corpus luteum. Around 7 o’clock the corpus luteum is already secreting a great amount of estrogen and progesterone and the endometrium thickens even more, concomitant lowering of FSH and LH occurs with the increasing of the ovarian hormones. Around 11 o’clock the reduced LH and FSH levels make the corpus luteum turn into the corpus albicans, the production of estrogen and progesterone ceases and the endometrium regresses. At 0 o’clock again (28th day) the endometrium desquamates and a new menstrual cycle begins.
