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Anaphase Promoting Complex (APC) is a protein degradation machinery necessary for proper mitosis of animal cells. If APC is defective in a human cell, which of the following is expected to occur ?
(1) Chromosomes will be fragmented
(2) Chromosomes will not segregate
(3) Recombination of chromosome arms will occur
(4) Chromosomes will not condense

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Best answer

The correct answer is (2)

During anaphase, Anaphase Promoting Complex (APC) is a protein necessary for separation of daughter chromosomes. A defective APC will cause the chromosomes fail to segregate during anaphase.

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