The following scheme describes the synthesis of a compound D (with sympathomimetic effects) whose skeleton consists of 2-phenylethylamine.
(1) What reagents were used in steps a, b, c, and d?
(2) Give the structural formulae of compounds B, C and D.
(3) Is it possible to prepare 3-hydroxyacetophenone from the reaction between phenol, acetylchloride and AlCl3? Give reasons for your answer.
(4) Give the formulae of the compounds that are formed by the reaction of compound C with a) 10% HCl and b) 10% NaOH.
(5) By the asterisk denote the chirality centre in the formula of compound D. 6) Give the spatial formula of enantiomer (R) of compound D.
