A synapse is the gap between the two neurons. Here the axon terminal of one neuron is in close proximity to the dendrite of the second neuron. When a nerve impulse reaches the knob like nerve ending of an axon, a tiny amount of a chemical substance is released in the synapse. This chemical substance is called as the neurotransmitter. At synapse the electrical signals converted into chemicals, that can easily cross over the gap and pass on to the next neurons where it again converted into electrical signals.