A. False At rest, O2 consumption (about 250 ml/min) is about 25 per cent of the total available.
B. True All but 3 of the 200 ml/l is combined with hemoglobin, the rest is dissolved.
C. False In anaemic hypoxia, cardiac output rises to compensate for the reduced oxygen content per litre of blood.
D. False If PO2 falls by 25 per cent from normal, there is relatively little change in the blood oxygen content.
E. False The extraction ratio rises as oxygen consumption rises, e.g. during exercise.