No, all chambers cannot experience systole simultaneously. Arteriole systole occurs first as it is directly connected to SA-node which initiates the cardiac impulse. This impulse is then discharged to atria and transmitted from atrial muscles to the ventricular muscles through atrio – ventricular node and Av – bundle. The impulse passes slowly across the AV-node and hence ventricular systole begins after the atrial systole is completed.