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What do you mean by the activation of an amino acid?

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In the cytoplasm, the amino acids occur in inactive form, hence they cannot take part in protein synthesis. The activation of amino acids is done by ATP which results in the formation of aminoacyl adenylate. This process is catalyses by specific enzymes & there is a specific enzyme for a specific amino acid. The enzyme recognises its own amino acid & finds out its own tRNA.

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