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List the functions of the following in Bioinformatics  

(i) ENTREZ

(ii) PDB

(iii) FASTA

(iv) MGD

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(i) ENTREZ: Integrated information database retrieval system of NCBI. Using Entrez system we can access literature, sequences (both proteins and nucleotides) and structures (3D). 

(ii) PDB: (Protein Data Bank): This database has sequence of those protein whose 3-D structures are known Sources: NCBI – USA; EBI, U.K. 

(iii) FASTA: 

• FASTA is a DNA and protein sequence alignment software package. 

• The current FASTA package contains programs for protein: protein, DNA: DNA, protein: translated DNA (with frame shifts), and ordered or unordered peptide searches. Recent versions of the FASTA package include special translated search algorithms that correctly handle frame shift errors (which six-frame-translated searches do not handle very well) when comparing nucleotide to protein sequence data.

(iv) Mouse Genome Database: MGD strives to provide an extensively integrated information resource with experimental details annotated from both literature and on-line genomic data sources.

MGD collaborates with other bioinformatics groups to curate a definitive set of information about the laboratory mouse.

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