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Write a note on various levels of protein organisation.

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The primary structure is linear arrangement of amino acids in a polypeptide chain. Secondary structure arises when various functional groups are exposed on outer surface of the molecular interaction by forming hydrogen bonds. This causes the amino acid chain to twist into coiled configuration called α – helix or to fold into a flat β – pleated sheets.

Tertiary protein structure arises when the secondary level proteins fold into globular structure called domains. Quaternary protein structure may be assumed by some complex proteins in which more than one polypeptide forms a large multiunit protein. The individual polypeptide chains of the protein are called subunits and the active protein itself is called a multimer.

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