Coronary heart disease occurs when the arteries are lined by atheroma. The build-up of atheroma contains cholesterol, fibres, dead muscle and platelets and is termed Atherosclerosis.
The cholesterol rich atheroma forms plaques in the inner lining of the arteries making them less elastic and reduces the blood flow. Plaque grows within the artery and tends to form blood clots, forming coronary thrombus. Thrombus in a coronary artery results in heart attack.