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What is the advantage of a four chambered heart in humans?

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The four-chambered heart allows us to send our deoxygenated blood to the lungs and our clean blood to the rest of the body without mixing the two. The blood coming from the left side of the heart is oxygenated and ready to fuel the muscles. The blood coming to the right side of the heart is collected from all over the body is deoxygenated and carried towards the lungs for oxygenation.

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