1. Transgenic mice are used in various research areas of cancer research.
2. Transgenic mice containing a particular oncogene (cancer causing gene) develop specific cancer.
3. They are used to study the relationship between oncogenes and cancer development, cancer treatment and prevention of malignancy.
4. The transgenic mouse model for the investigation of the breast cancer was developed in the laboratory of Philip Leder in Harvard (USA).
5. Transgenic mice containing oncogenes myc and ras were analyzed to find out role of these genes in the development of breast cancer.
