HIV (Human immune deficiency virus) enters into macrophages after getting in human body HIV multiplies first in macrophages and then in helper T cells or lymphocytes.
Events that occur in the human host after the entry of HIV:
- After entering the human body, the HIV virus attacks and enters the macrophages.
- Inside the macrophages, the RNA of the virus replicates with the help of enzyme reverse transcriptase and give rise to viral DNA.
- Then, this viral DNA incorporates into the host cell DNA uses raw materials and infected cell machinery and directs the synthesis of virus particles.
- At the same time, HIV enters the helper T-Jymphocytes, replicates and produce progenies.
- As a result, T-lymphocytes start decreasing in number and immune response of the person becomes weak.