Question

The association of histone H₁ with a nucleosome indicate

(a) transcription is occurring 

(b) DNA replication is occurring 

(c) the DNA is condensed into chromatin fibre 

(d) the DNA double helix is exposed

Answer 1

Correct option (c) the DNA is condensed into chromatin fibre

Explanation

The association of H₁ histone with nucleosome indicates that DNA remains in its condensed form. Concept Enhancer In eukaryotes, DNA packaging is carried out with the help of histone proteins. Nucleosome is the unit of compaction. Its core consists of four pairs of histones (H₂A, H₂B, H₃ and H₄). The linker DNA, consisting of H₁ histone connects two adjacent nucleosomes. 

They together constitute chromatosome. It gives rise to a chromatin fibre after further condensation.