Question

CATH is a combination of manual curation and automated procedure, which makes the process less subjective.

(a) True

(b) False

The question was posed to me in a national level competition.

Origin of the question is Protein Structure Classification topic in division Structural Bioinformatics of Bioinformatics

Answer 1

The correct choice is (a) True

The best explanation: For example, in defining domains, CATH first relies on the consensus of three different algorithms to recognize domains. When the computer programs disagree, human intervention will take place. In addition, the extra Architecture level in CATH makes the structure classification more continuous. The drawback of the systems is that the fixed thresholds in structural comparison may make assignment less accurate.