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How many post-translational modifications occur in the pre-rRNA (primary transcript)?

(a) 1

(b) 2

(c) 3

(d) 4

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Right answer is (b) 2

Explanation: Two types of post-translational modifications are characteristic of pre-rRNA, large number of methylated nucleotides and pseudouridine residues. These make the pre-rRNA peculiar and contrasting from other primary RNA transcripts.

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