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Which of the following disease is caused by a chromosomal translocation?

(a) Chronic myelogenous leukemia

(b) Hodgkin’s B-cell lymphoma

(c) Alzheimer’s disease

(d) Parkinson’s disease

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Right answer is (a) Chronic myelogenous leukemia

For explanation: Chronic myelogenous leukemia is caused by a chromosomal translocation that brings together the proto-oncogene (ABL) in contact with another gene (BCR) to form a chimeric gene (BCR ABL).

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