Question

Complement and antibodies each have specialized features and functions, but some are shared between them. These include:

1. Recruitment to sites of infection.
2. Formation of immune complexes.

1. Option 1 is correct
2. Option 2 is correct
3. Both are correct
4. Both are incorrect

Answer 1

Correct Answer - Option 3 : Both are correct

The correct answer is 3 i.e. Both are correct.

Explanation:

• Complement and antibodies each have specialized features and functions, but some are shared between them. These include:
  • Recruitment to sites of infection: Both are types of soluble molecules that circulate in the blood, but which can be recruited to sites of infection because local inflammatory responses increase the permeability of the endothelium, allowing them to cross into extravascular tissue spaces.
  • Formation of immune complexes: Both can bind to soluble antigens to form complexes that may induce inflammation.
  • Opsonization: This is the process of coating microbes, to enhance their uptake and subsequent elimination by phagocytes. Microbes coated with complement or antibodies are directed to specialized receptors, called opsonic receptors. These are respectively the complement receptors and
    the FC receptors (FcRs); there are several types of each.
  • Enhancing adaptive immunity: Components of complement and antibodies, when bound to antigens, can enhance different types of adaptive immune responses.