You can create an Aurora DB cluster via the AWS Management Console, AWS CLI, or AWS SDKs. Here's an example using AWS CLI:
aws rds create-db-cluster \
--db-cluster-identifier my-aurora-cluster \
--engine aurora-mysql \
--master-username myadmin \
--master-user-password mypassword \
--db-subnet-group-name my-subnet-group \
--vpc-security-group-ids sg-12345678