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The most likely lethal mutation is (A) Substitution of adenine for cytosine (B) Insertion of one nucleotide

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The most likely lethal mutation is 

(A) Substitution of adenine for cytosine 

(B) Insertion of one nucleotide 

(C) Deletion of three nucleotides 

(D) Substitution of cytosine for guanine

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(B) Insertion of one nucleotide

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