DNA is a polymer of nucleotides which are linked to each other by 3’-5’ phosphodiester bond. To prevent polymerisation of nucleotides, which of the following modifications would you choose?
a. Replace purine with pyrimidines
b. Remove/Replace 3' OH group in deoxy ribose
c. Remove/Replace 2' OH group with some other group in deoxy ribose
d. Both ‘B’ and ‘C’
