The transformation of normal cells into cancerous neoplastie cells is induced by physical clinical and biological agents collectively called careinogenes, they lose the property of contact inhibition. Differences between viral oncogenes and cellular oncogenes are
- Viral oncogenes are the genes present in I the oncogenic virus which affect oncogenic transformation of the cells they infect.
- Cellular oncogenes are the genes presents in normal cells and code for growth factors, when activated under certain condition can cause oncogenic transformation of the cell.