Question

The prediction programs are thus designed using the energy minimization principle.

(a) True

(b) False

The question was asked in unit test.

Asked question is from Ab Initio Protein Structural Prediction & Homology Modeling in division Protein Tertiary Structure Prediction of Bioinformatics

Answer 1

The correct choice is (a) True

To elaborate: Current ab initio algorithms are not yet able to accurately simulate the protein folding process. They work by using some type of heuristics. Because the native state of a protein structure is near energy minimum, the prediction programs are thus designed using the energy minimization principle.