Spermatogenesis starts at the age of puberty due to significant increase in the secretion of gonadotropin releasing hormone (GnRH). This is a hypothalamic hormone.
The increased levels of GnRH then act at the anterior pituitary gland and stimulate secretion of two gonadotropins – luteinising hormone (LH) and follicle stimulating hormone (FSH).
LH acts at the Leydig cells and stimulates synthesis and secretion of androgens. Androgens, in turn, stimulate the process of spermatogenesis.
FSH acts on the Sertoli cells and stimulates secretion of some factors which help in the process of spermiogenesis.
